BDBM50241330 CHEMBL398829::N-(4-(2-((1-isobutylpiperidin-4-yl)methylamino)-6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamide

SMILES: CC(C)CN1CCC(CNc2nc(Oc3cccc4sc(NC(C)=O)nc34)cc(n2)-c2ccc(cc2)C(F)(F)F)CC1

InChI Key: InChIKey=WWYOJWMTSUQDTO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50241330 (CHEMBL398829 | N-(4-(2-((1-isobutylpiperidin-4-yl)...) Show SMILES CC(C)CN1CCC(CNc2nc(Oc3cccc4sc(NC(C)=O)nc34)cc(n2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C30H33F3N6O2S/c1-18(2)17-39-13-11-20(12-14-39)16-34-28-36-23(21-7-9-22(10-8-21)30(31,32)33)15-26(37-28)41-24-5-4-6-25-27(24)38-29(42-25)35-19(3)40/h4-10,15,18,20H,11-14,16-17H2,1-3H3,(H,34,36,37)(H,35,38,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed inhibition of capsaicin induced calcium influx				Bioorg Med Chem Lett 17: 6539-45 (2007) Article DOI: 10.1016/j.bmcl.2007.09.080 BindingDB Entry DOI: 10.7270/Q2FX7961
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50241330 (CHEMBL398829 | N-(4-(2-((1-isobutylpiperidin-4-yl)...) Show SMILES CC(C)CN1CCC(CNc2nc(Oc3cccc4sc(NC(C)=O)nc34)cc(n2)-c2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C30H33F3N6O2S/c1-18(2)17-39-13-11-20(12-14-39)16-34-28-36-23(21-7-9-22(10-8-21)30(31,32)33)15-26(37-28)41-24-5-4-6-25-27(24)38-29(42-25)35-19(3)40/h4-10,15,18,20H,11-14,16-17H2,1-3H3,(H,34,36,37)(H,35,38,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed inhibition of acid induced calcium influx				Bioorg Med Chem Lett 17: 6539-45 (2007) Article DOI: 10.1016/j.bmcl.2007.09.080 BindingDB Entry DOI: 10.7270/Q2FX7961
					More data for this Ligand-Target Pair