BDBM50241489 (Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-4-one::5-(3-methoxybenzylidene)-2-thioxothiazolidin-4-one::CHEMBL402427

SMILES: COc1cccc(C=C2SC(S)=NC2=O)c1

InChI Key: InChIKey=ZXBRDIMYFRPBGK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (ALR2) (Bos taurus (Cattle))	BDBM50241489 ((Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-...) Show SMILES COc1cccc(C=C2SC(S)=NC2=O)c1 |w:7.6,c:11| Show InChI InChI=1S/C11H9NO2S2/c1-14-8-4-2-3-7(5-8)6-9-10(13)12-11(15)16-9/h2-6H,1H3,(H,12,13,15)	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysis				Bioorg Med Chem Lett 21: 200-3 (2010) Article DOI: 10.1016/j.bmcl.2010.11.041 BindingDB Entry DOI: 10.7270/Q2ZP46C4
					More data for this Ligand-Target Pair
Arylamine N-acetyltransferase 1 (Homo sapiens (Human))	BDBM50241489 ((Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-...) Show SMILES COc1cccc(C=C2SC(S)=NC2=O)c1 |w:7.6,c:11| Show InChI InChI=1S/C11H9NO2S2/c1-14-8-4-2-3-7(5-8)6-9-10(13)12-11(15)16-9/h2-6H,1H3,(H,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method				Bioorg Med Chem 17: 905-18 (2009) Article DOI: 10.1016/j.bmc.2008.11.032 BindingDB Entry DOI: 10.7270/Q2PZ58Q3
					More data for this Ligand-Target Pair