BDBM50241507 CHEMBL4083732

SMILES: Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC(C)(N)CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=WXYADTLUDIHCOC-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241507 (CHEMBL4083732) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC(C)(N)CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C22H26N4O3S/c1-17-3-9-20(10-4-17)30(28,29)26(19-7-5-18(15-23)6-8-19)16-21(27)25-13-11-22(2,24)12-14-25/h3-10H,11-14,16,24H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241507 (CHEMBL4083732) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC(C)(N)CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C22H26N4O3S/c1-17-3-9-20(10-4-17)30(28,29)26(19-7-5-18(15-23)6-8-19)16-21(27)25-13-11-22(2,24)12-14-25/h3-10H,11-14,16,24H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair