BDBM50241518 CHEMBL4093280

SMILES: Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1cccnc1)c1ccc(cc1)C#N

InChI Key: InChIKey=PDHMVKPYBJAZQZ-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241518 (CHEMBL4093280) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C21H18N4O3S/c1-16-4-10-20(11-5-16)29(27,28)25(19-8-6-17(13-22)7-9-19)15-21(26)24-18-3-2-12-23-14-18/h2-12,14H,15H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241518 (CHEMBL4093280) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C21H18N4O3S/c1-16-4-10-20(11-5-16)29(27,28)25(19-8-6-17(13-22)7-9-19)15-21(26)24-18-3-2-12-23-14-18/h2-12,14H,15H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair