BindingDB logo
myBDB logout

BDBM50241541 CHEMBL4087749

SMILES: O\N=c1/cc(oc2ccccc12)-c1cc2ccccc2o1

InChI Key: InChIKey=NVYDWNUSCONKLU-QGOAFFKASA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241541   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50241541
PNG
(CHEMBL4087749)
Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2ccccc2o1
Show InChI InChI=1S/C17H11NO3/c19-18-13-10-17(21-15-8-4-2-6-12(13)15)16-9-11-5-1-3-7-14(11)20-16/h1-10,19H/b18-13+
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Prexton Therapeutics

Curated by ChEMBL


Assay Description
Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...


J Med Chem 60: 8515-8537 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00991
BindingDB Entry DOI: 10.7270/Q2GF0WNQ
More data for this
Ligand-Target Pair