BDBM50241541 CHEMBL4087749
SMILES: O\N=c1/cc(oc2ccccc12)-c1cc2ccccc2o1
InChI Key: InChIKey=NVYDWNUSCONKLU-QGOAFFKASA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50241541 (CHEMBL4087749) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Prexton Therapeutics Curated by ChEMBL | Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in... | J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ | |||||||||||
More data for this Ligand-Target Pair |