BDBM50242128 CHEMBL511822::Taraxerol, 8::taraxerol
SMILES: CC1(C)CC[C@]2(C)CC=C3[C@]4(C)CC[C@H]5C(C)(C)[C@@H](O)CC[C@]5(C)[C@H]4CC[C@@]3(C)[C@@H]2C1
InChI Key: InChIKey=GGGUGZHBAOMSFJ-GADYQYKKSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric Oxide Synthase, inducible (Mus musculus (mouse)) | BDBM50242128 (CHEMBL511822 | Taraxerol, 8 | taraxerol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cheng Kung University Curated by ChEMBL | Assay Description Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cells | Bioorg Med Chem 16: 9867-70 (2008) Article DOI: 10.1016/j.bmc.2008.09.021 BindingDB Entry DOI: 10.7270/Q2125TK2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ghrelin O-acyltransferase (Homo sapiens (Human)) | BDBM50242128 (CHEMBL511822 | Taraxerol, 8 | taraxerol) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Syracuse University | Assay Description Assays were performed with ~100 μg of membrane protein, as determined by a Bradford assay. The membrane fraction was preincubated with 1 μM met... | Biochemistry 56: 919-931 (2017) Article DOI: 10.1021/acs.biochem.6b01008 BindingDB Entry DOI: 10.7270/Q270808D | |||||||||||
More data for this Ligand-Target Pair |