BDBM50242194 CHEMBL4079465

SMILES: Cc1cccc(OCCOc2nc3ccccc3nc2CCC(O)=O)c1

InChI Key: InChIKey=GXKFVYJFLPNQSQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50242194 (CHEMBL4079465) Show SMILES Cc1cccc(OCCOc2nc3ccccc3nc2CCC(O)=O)c1 Show InChI InChI=1S/C20H20N2O4/c1-14-5-4-6-15(13-14)25-11-12-26-20-18(9-10-19(23)24)21-16-7-2-3-8-17(16)22-20/h2-8,13H,9-12H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of FITC-labeled RLRGG peptide from N-terminal His6-tagged HDAC6 zinc-finger ubiquitin binding domain (1109 to 1215 residues)(unknown ori...				J Med Chem 60: 9090-9096 (2017) Article DOI: 10.1021/acs.jmedchem.7b00933 BindingDB Entry DOI: 10.7270/Q2M32Z5T
					More data for this Ligand-Target Pair