BDBM50242395 CHEMBL4079798

SMILES: Cc1nc2c(ncnc2n1Cc1ccc(cc1)-c1ccnc(C)c1)N1CCOCC1

InChI Key: InChIKey=GILPUSUJJCFBRD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50242395 (CHEMBL4079798) Show SMILES Cc1nc2c(ncnc2n1Cc1ccc(cc1)-c1ccnc(C)c1)N1CCOCC1 Show InChI InChI=1S/C23H24N6O/c1-16-13-20(7-8-24-16)19-5-3-18(4-6-19)14-29-17(2)27-21-22(25-15-26-23(21)29)28-9-11-30-12-10-28/h3-8,13,15H,9-12,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Nanchang University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDE10A1 (2 to 789 residues) expressed in baculovirus infected Sf9 cells using fluorescein-label...				Bioorg Med Chem 25: 3315-3329 (2017) Article DOI: 10.1016/j.bmc.2017.04.019 BindingDB Entry DOI: 10.7270/Q25X2CB8
					More data for this Ligand-Target Pair