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SMILES: C[C@H](c1cccc2CCNCc12)n1c2cc(F)c(cc2oc1=O)S(=O)(=O)Nc1cccc(F)n1

InChI Key: InChIKey=ZDJCJHFIEDESCL-CYBMUJFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242506   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50242506
PNG
(CHEMBL4077789)
Show SMILES C[C@H](c1cccc2CCNCc12)n1c2cc(F)c(cc2oc1=O)S(=O)(=O)Nc1cccc(F)n1 |r|
Show InChI InChI=1S/C23H20F2N4O4S/c1-13(15-5-2-4-14-8-9-26-12-16(14)15)29-18-10-17(24)20(11-19(18)33-23(29)30)34(31,32)28-22-7-3-6-21(25)27-22/h2-7,10-11,13,26H,8-9,12H2,1H3,(H,27,28)/t13-/m1/s1
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Similars
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Merck& Co.

Curated by ChEMBL


Assay Description
Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...

Bioorg Med Chem Lett 27: 2683-2688 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.040
BindingDB Entry DOI: 10.7270/Q2SN0CD7
More data for this
Ligand-Target Pair