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BDBM50242521 CHEMBL4072687

SMILES: COc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1

InChI Key: InChIKey=ZMCPSBGYMYBBRW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242521   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50242521
PNG
(CHEMBL4072687)
Show SMILES COc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1
Show InChI InChI=1S/C19H19N5O2/c1-10-7-14-13(8-15(10)25)16-17(23-19(20)24-18(16)22-14)21-9-11-3-5-12(26-2)6-4-11/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 5.95E+3n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys...

Bioorg Med Chem Lett 27: 2708-2712 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT
More data for this
Ligand-Target Pair