BDBM50242527 CHEMBL4061797

SMILES: COc1ccc(CNc2nc(N)nc3[nH]c4ccc(O)cc4c23)cc1OC

InChI Key: InChIKey=QQXOSHNOICWNIG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50242527 (CHEMBL4061797) Show SMILES COc1ccc(CNc2nc(N)nc3[nH]c4ccc(O)cc4c23)cc1OC Show InChI InChI=1S/C19H19N5O3/c1-26-14-6-3-10(7-15(14)27-2)9-21-17-16-12-8-11(25)4-5-13(12)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys...				Bioorg Med Chem Lett 27: 2708-2712 (2017) Article DOI: 10.1016/j.bmcl.2017.04.053 BindingDB Entry DOI: 10.7270/Q2J67KBT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50242527 (CHEMBL4061797) Show SMILES COc1ccc(CNc2nc(N)nc3[nH]c4ccc(O)cc4c23)cc1OC Show InChI InChI=1S/C19H19N5O3/c1-26-14-6-3-10(7-15(14)27-2)9-21-17-16-12-8-11(25)4-5-13(12)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal...				Bioorg Med Chem Lett 27: 2708-2712 (2017) Article DOI: 10.1016/j.bmcl.2017.04.053 BindingDB Entry DOI: 10.7270/Q2J67KBT
					More data for this Ligand-Target Pair