BDBM50242568 4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cycloheptylpiperazine-1-carboxamide::CHEMBL488031

SMILES: Cc1ccccc1C(N1CCN(CC1)C(=O)NC1CCCCCC1)c1ccc(Cl)cc1

InChI Key: InChIKey=AMOQRGVXFGDBST-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50242568 (4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cycloheptylp...) Show SMILES Cc1ccccc1C(N1CCN(CC1)C(=O)NC1CCCCCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H34ClN3O/c1-20-8-6-7-11-24(20)25(21-12-14-22(27)15-13-21)29-16-18-30(19-17-29)26(31)28-23-9-4-2-3-5-10-23/h6-8,11-15,23,25H,2-5,9-10,16-19H2,1H3,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHOK1 cells by luciferase assay				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50242568 (4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cycloheptylp...) Show SMILES Cc1ccccc1C(N1CCN(CC1)C(=O)NC1CCCCCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H34ClN3O/c1-20-8-6-7-11-24(20)25(21-12-14-22(27)15-13-21)29-16-18-30(19-17-29)26(31)28-23-9-4-2-3-5-10-23/h6-8,11-15,23,25H,2-5,9-10,16-19H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebella membrane				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50242568 (4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cycloheptylp...) Show SMILES Cc1ccccc1C(N1CCN(CC1)C(=O)NC1CCCCCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H34ClN3O/c1-20-8-6-7-11-24(20)25(21-12-14-22(27)15-13-21)29-16-18-30(19-17-29)26(31)28-23-9-4-2-3-5-10-23/h6-8,11-15,23,25H,2-5,9-10,16-19H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]WIN55212-2 from human CB2 receptor expressed in CHOK1 cells				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair