BDBM50242570 CHEMBL4081762

SMILES: CC(C)c1cc(no1)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=ZQRRVNZLRRZHSQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Survival motor neuron protein (Homo sapiens)	BDBM50242570 (CHEMBL4081762) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H13ClN2O2/c1-8(2)12-7-11(16-18-12)13(17)15-10-5-3-9(14)4-6-10/h3-8H,1-2H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair