BDBM50242717 (E)-3-(4-((E)-3-(2,6-difluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide::CHEMBL461492

SMILES: Cn1cc(\C=C\C(=O)c2c(F)cccc2F)cc1\C=C\C(=O)NO

InChI Key: InChIKey=HGCOAESDMUAKHV-KQQUZDAGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50242717 ((E)-3-(4-((E)-3-(2,6-difluorophenyl)-3-oxoprop-1-e...) Show SMILES Cn1cc(\C=C\C(=O)c2c(F)cccc2F)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H14F2N2O3/c1-21-10-11(9-12(21)6-8-16(23)20-24)5-7-15(22)17-13(18)3-2-4-14(17)19/h2-10,24H,1H3,(H,20,23)/b7-5+,8-6+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	807	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 1B				Eur J Med Chem 43: 621-32 (2008) Article DOI: 10.1016/j.ejmech.2007.05.004 BindingDB Entry DOI: 10.7270/Q28K78V4
					More data for this Ligand-Target Pair