BDBM50242812 2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-propyl-3,5-bis(trifluoromethyl)phenylsulfonamido)phenyl)amino)-2-oxoacetic acid::CHEMBL501289

SMILES: CCCN(c1ccc(cc1)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)C(O)=O)S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=LREXPYFOIVEFBG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM50242812 (2-((3,5-bis(trifluoromethyl)benzyl)(4-(N-propyl-3,...) Show SMILES CCCN(c1ccc(cc1)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)C(O)=O)S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C28H20F12N2O5S/c1-2-7-42(48(46,47)22-12-18(27(35,36)37)11-19(13-22)28(38,39)40)21-5-3-20(4-6-21)41(23(43)24(44)45)14-15-8-16(25(29,30)31)10-17(9-15)26(32,33)34/h3-6,8-13H,2,7,14H2,1H3,(H,44,45)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of human PAI1 by chromogenic assay				Eur J Med Chem 43: 880-4 (2008) Article DOI: 10.1016/j.ejmech.2007.05.011 BindingDB Entry DOI: 10.7270/Q25Q4VWX
					More data for this Ligand-Target Pair