BDBM50242922 1-[1-(3-Methoxyphenyl)-2-(4-methyl-1-piperazinyl)ethyl]cyclohexanol Dihydrochloride::CHEMBL469459

SMILES: COc1cccc(c1)C(CN1CCN(C)CC1)C1(O)CCCCC1

InChI Key: InChIKey=WWUZCWXKLHVLMN-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50242922 (1-[1-(3-Methoxyphenyl)-2-(4-methyl-1-piperazinyl)e...) Show SMILES COc1cccc(c1)C(CN1CCN(C)CC1)C1(O)CCCCC1 Show InChI InChI=1S/C20H32N2O2/c1-21-11-13-22(14-12-21)16-19(20(23)9-4-3-5-10-20)17-7-6-8-18(15-17)24-2/h6-8,15,19,23H,3-5,9-14,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	514	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cells				J Med Chem 51: 4038-49 (2008) Article DOI: 10.1021/jm8002262 BindingDB Entry DOI: 10.7270/Q2TB16PB
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50242922 (1-[1-(3-Methoxyphenyl)-2-(4-methyl-1-piperazinyl)e...) Show SMILES COc1cccc(c1)C(CN1CCN(C)CC1)C1(O)CCCCC1 Show InChI InChI=1S/C20H32N2O2/c1-21-11-13-22(14-12-21)16-19(20(23)9-4-3-5-10-20)17-7-6-8-18(15-17)24-2/h6-8,15,19,23H,3-5,9-14,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cells				J Med Chem 51: 4038-49 (2008) Article DOI: 10.1021/jm8002262 BindingDB Entry DOI: 10.7270/Q2TB16PB
					More data for this Ligand-Target Pair