BDBM50242946 CHEMBL4062278

SMILES: CN(C)C(=O)COc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1

InChI Key: InChIKey=FMJSNTDMWQHNSZ-OAHLLOKOSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242946 (CHEMBL4062278) Show SMILES CN(C)C(=O)COc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C20H24N6O3/c1-24(2)18(27)13-29-19-10-17(20(28)25-9-3-4-15(22)12-25)23-26(19)16-7-5-14(11-21)6-8-16/h5-8,10,15H,3-4,9,12-13,22H2,1-2H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242946 (CHEMBL4062278) Show SMILES CN(C)C(=O)COc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C20H24N6O3/c1-24(2)18(27)13-29-19-10-17(20(28)25-9-3-4-15(22)12-25)23-26(19)16-7-5-14(11-21)6-8-16/h5-8,10,15H,3-4,9,12-13,22H2,1-2H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair