null

SMILES: CC(Oc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1)C(N)=O

InChI Key: InChIKey=GXWUBLOAKXBSNV-TYZXPVIJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242947 (CHEMBL4083993) Show SMILES CC(Oc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1)C(N)=O |r| Show InChI InChI=1S/C19H22N6O3/c1-12(18(22)26)28-17-9-16(19(27)24-8-2-3-14(21)11-24)23-25(17)15-6-4-13(10-20)5-7-15/h4-7,9,12,14H,2-3,8,11,21H2,1H3,(H2,22,26)/t12?,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242947 (CHEMBL4083993) Show SMILES CC(Oc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1)C(N)=O |r| Show InChI InChI=1S/C19H22N6O3/c1-12(18(22)26)28-17-9-16(19(27)24-8-2-3-14(21)11-24)23-25(17)15-6-4-13(10-20)5-7-15/h4-7,9,12,14H,2-3,8,11,21H2,1H3,(H2,22,26)/t12?,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair