Found 3 hits for monomerid = 50243139 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50243139
(3beta-(4-Methylphenyl)-2beta-[3'-(4-fluorobenzyl)i...)Show SMILES CN1C2CCC1[C@H]([C@H](C2)c1ccc(C)cc1)c1cc(Cc2ccc(F)cc2)no1 |r,TLB:16:6:1:4.3| Show InChI InChI=1S/C25H27FN2O/c1-16-3-7-18(8-4-16)22-15-21-11-12-23(28(21)2)25(22)24-14-20(27-29-24)13-17-5-9-19(26)10-6-17/h3-10,14,21-23,25H,11-13,15H2,1-2H3/t21?,22-,23?,25+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 113 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]paroxetine from 5HTT |
Bioorg Med Chem 16: 6682-8 (2008)
Article DOI: 10.1016/j.bmc.2008.05.073 BindingDB Entry DOI: 10.7270/Q2NK3FX0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50243139
(3beta-(4-Methylphenyl)-2beta-[3'-(4-fluorobenzyl)i...)Show SMILES CN1C2CCC1[C@H]([C@H](C2)c1ccc(C)cc1)c1cc(Cc2ccc(F)cc2)no1 |r,TLB:16:6:1:4.3| Show InChI InChI=1S/C25H27FN2O/c1-16-3-7-18(8-4-16)22-15-21-11-12-23(28(21)2)25(22)24-14-20(27-29-24)13-17-5-9-19(26)10-6-17/h3-10,14,21-23,25H,11-13,15H2,1-2H3/t21?,22-,23?,25+/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 454 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from NET |
Bioorg Med Chem 16: 6682-8 (2008)
Article DOI: 10.1016/j.bmc.2008.05.073 BindingDB Entry DOI: 10.7270/Q2NK3FX0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50243139
(3beta-(4-Methylphenyl)-2beta-[3'-(4-fluorobenzyl)i...)Show SMILES CN1C2CCC1[C@H]([C@H](C2)c1ccc(C)cc1)c1cc(Cc2ccc(F)cc2)no1 |r,TLB:16:6:1:4.3| Show InChI InChI=1S/C25H27FN2O/c1-16-3-7-18(8-4-16)22-15-21-11-12-23(28(21)2)25(22)24-14-20(27-29-24)13-17-5-9-19(26)10-6-17/h3-10,14,21-23,25H,11-13,15H2,1-2H3/t21?,22-,23?,25+/m1/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]WIN-35428 from DAT |
Bioorg Med Chem 16: 6682-8 (2008)
Article DOI: 10.1016/j.bmc.2008.05.073 BindingDB Entry DOI: 10.7270/Q2NK3FX0 |
More data for this Ligand-Target Pair | |