BDBM50243154 CHEMBL487690::cis-3-(4-chlorophenoxy)-N,N-dimethyl-2,3-dihydro-1H-inden-1-amine

SMILES: CN(C)[C@@H]1C[C@H](Oc2ccc(Cl)cc2)c2ccccc12

InChI Key: InChIKey=NNOXYEGAVKKWOL-SJORKVTESA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50243154 (CHEMBL487690 | cis-3-(4-chlorophenoxy)-N,N-dimethy...) Show SMILES CN(C)[C@@H]1C[C@H](Oc2ccc(Cl)cc2)c2ccccc12 |r| Show InChI InChI=1S/C17H18ClNO/c1-19(2)16-11-17(15-6-4-3-5-14(15)16)20-13-9-7-12(18)8-10-13/h3-10,16-17H,11H2,1-2H3/t16-,17+/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at human DAT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50243154 (CHEMBL487690 | cis-3-(4-chlorophenoxy)-N,N-dimethy...) Show SMILES CN(C)[C@@H]1C[C@H](Oc2ccc(Cl)cc2)c2ccccc12 |r| Show InChI InChI=1S/C17H18ClNO/c1-19(2)16-11-17(15-6-4-3-5-14(15)16)20-13-9-7-12(18)8-10-13/h3-10,16-17H,11H2,1-2H3/t16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50243154 (CHEMBL487690 | cis-3-(4-chlorophenoxy)-N,N-dimethy...) Show SMILES CN(C)[C@@H]1C[C@H](Oc2ccc(Cl)cc2)c2ccccc12 |r| Show InChI InChI=1S/C17H18ClNO/c1-19(2)16-11-17(15-6-4-3-5-14(15)16)20-13-9-7-12(18)8-10-13/h3-10,16-17H,11H2,1-2H3/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair