BDBM50243157 CHEMBL521392::cis-N,N-dimethyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine

SMILES: CN(C)[C@@H]1C[C@H](Oc2ccccc2C)c2ccccc12

InChI Key: InChIKey=NBLMTDPDGYITGF-AEFFLSMTSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50243157 (CHEMBL521392 | cis-N,N-dimethyl-3-(o-tolyloxy)-2,3...) Show SMILES CN(C)[C@@H]1C[C@H](Oc2ccccc2C)c2ccccc12 |r| Show InChI InChI=1S/C18H21NO/c1-13-8-4-7-11-17(13)20-18-12-16(19(2)3)14-9-5-6-10-15(14)18/h4-11,16,18H,12H2,1-3H3/t16-,18+/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at human DAT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50243157 (CHEMBL521392 | cis-N,N-dimethyl-3-(o-tolyloxy)-2,3...) Show SMILES CN(C)[C@@H]1C[C@H](Oc2ccccc2C)c2ccccc12 |r| Show InChI InChI=1S/C18H21NO/c1-13-8-4-7-11-17(13)20-18-12-16(19(2)3)14-9-5-6-10-15(14)18/h4-11,16,18H,12H2,1-3H3/t16-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50243157 (CHEMBL521392 | cis-N,N-dimethyl-3-(o-tolyloxy)-2,3...) Show SMILES CN(C)[C@@H]1C[C@H](Oc2ccccc2C)c2ccccc12 |r| Show InChI InChI=1S/C18H21NO/c1-13-8-4-7-11-17(13)20-18-12-16(19(2)3)14-9-5-6-10-15(14)18/h4-11,16,18H,12H2,1-3H3/t16-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair