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BDBM50243175 ((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)phenyl)-1,3a,4,6a-tetrahydrocyclopenta[c]pyrrol-2(1H)-yl)(phenyl)methanone::CHEMBL529892

SMILES: C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)c1ccccc1

InChI Key: InChIKey=CXSRZRVFUKIDBY-UGIARPQZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243175   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50243175
PNG
(((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)et...)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)c1ccccc1 |r,t:16|
Show InChI InChI=1S/C27H32N2O/c1-20-6-5-16-28(20)17-15-21-9-11-22(12-10-21)25-14-13-24-18-29(19-26(24)25)27(30)23-7-3-2-4-8-23/h2-4,7-12,14,20,24,26H,5-6,13,15-19H2,1H3/t20-,24+,26-/m1/s1
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Similars
Article
PubMed
 3n/an/an/an/an/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane

Bioorg Med Chem Lett 18: 4133-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.086
BindingDB Entry DOI: 10.7270/Q2C82942
More data for this
Ligand-Target Pair