BDBM50243187 (S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-ylamino)hexan-1-one::CHEMBL487872

SMILES: N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1

InChI Key: InChIKey=KDQVIWLGGYIZDX-QHCPKHFHSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50243187 ((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...) Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of DPP2 (unknown origin)				Bioorg Med Chem Lett 18: 4159-62 (2008) Article DOI: 10.1016/j.bmcl.2008.05.079 BindingDB Entry DOI: 10.7270/Q2KS6RC4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50243187 ((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...) Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of DPP9 (unknown origin)				Bioorg Med Chem Lett 18: 4159-62 (2008) Article DOI: 10.1016/j.bmcl.2008.05.079 BindingDB Entry DOI: 10.7270/Q2KS6RC4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50243187 ((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...) Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				Bioorg Med Chem Lett 18: 4159-62 (2008) Article DOI: 10.1016/j.bmcl.2008.05.079 BindingDB Entry DOI: 10.7270/Q2KS6RC4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50243187 ((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...) Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1 |r| Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				Bioorg Med Chem Lett 18: 4159-62 (2008) Article DOI: 10.1016/j.bmcl.2008.05.079 BindingDB Entry DOI: 10.7270/Q2KS6RC4
					More data for this Ligand-Target Pair