BDBM50243269 CHEMBL453061::cis-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-1-amine

SMILES: Cc1ccccc1O[C@H]1CC[C@@H](N)c2ccccc12

InChI Key: InChIKey=WZVJYHZPOKMITP-WBVHZDCISA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50243269 (CHEMBL453061 | cis-4-(o-tolyloxy)-1,2,3,4-tetrahyd...) Show SMILES Cc1ccccc1O[C@H]1CC[C@@H](N)c2ccccc12 |r| Show InChI InChI=1S/C17H19NO/c1-12-6-2-5-9-16(12)19-17-11-10-15(18)13-7-3-4-8-14(13)17/h2-9,15,17H,10-11,18H2,1H3/t15-,17+/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at human DAT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50243269 (CHEMBL453061 | cis-4-(o-tolyloxy)-1,2,3,4-tetrahyd...) Show SMILES Cc1ccccc1O[C@H]1CC[C@@H](N)c2ccccc12 |r| Show InChI InChI=1S/C17H19NO/c1-12-6-2-5-9-16(12)19-17-11-10-15(18)13-7-3-4-8-14(13)17/h2-9,15,17H,10-11,18H2,1H3/t15-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50243269 (CHEMBL453061 | cis-4-(o-tolyloxy)-1,2,3,4-tetrahyd...) Show SMILES Cc1ccccc1O[C@H]1CC[C@@H](N)c2ccccc12 |r| Show InChI InChI=1S/C17H19NO/c1-12-6-2-5-9-16(12)19-17-11-10-15(18)13-7-3-4-8-14(13)17/h2-9,15,17H,10-11,18H2,1H3/t15-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
					More data for this Ligand-Target Pair