BDBM50243939 (cis)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicyclo[3.1.0]hexane::CHEMBL448893

SMILES: C[C@@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=AYVHIUIIRXDSCH-GMEUVTARSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transporter (Rattus norvegicus (rat))	BDBM50243939 ((cis)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicycl...) Show SMILES C[C@@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C12H13Cl2N/c1-7-9-5-15-6-12(7,9)8-2-3-10(13)11(14)4-8/h2-4,7,9,15H,5-6H2,1H3/t7-,9-,12+/m1/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at NET in rat brain synaptosome				Bioorg Med Chem Lett 18: 3682-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.077 BindingDB Entry DOI: 10.7270/Q26974G5
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50243939 ((cis)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicycl...) Show SMILES C[C@@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C12H13Cl2N/c1-7-9-5-15-6-12(7,9)8-2-3-10(13)11(14)4-8/h2-4,7,9,15H,5-6H2,1H3/t7-,9-,12+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at cloned DAT in rat brain synaptosome				Bioorg Med Chem Lett 18: 3682-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.077 BindingDB Entry DOI: 10.7270/Q26974G5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50243939 ((cis)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicycl...) Show SMILES C[C@@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C12H13Cl2N/c1-7-9-5-15-6-12(7,9)8-2-3-10(13)11(14)4-8/h2-4,7,9,15H,5-6H2,1H3/t7-,9-,12+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at SERT in rat brain synaptosome				Bioorg Med Chem Lett 18: 3682-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.077 BindingDB Entry DOI: 10.7270/Q26974G5
					More data for this Ligand-Target Pair