BDBM50243992 (trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3.1.0]hexane::CHEMBL453576

SMILES: C[C@H]1NC[C@]2(C[C@@H]12)c1cccs1

InChI Key: InChIKey=BQORSRVGJSQEKY-WEDXCCLWSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transporter (Rattus norvegicus (rat))	BDBM50243992 ((trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3...) Show SMILES C[C@H]1NC[C@]2(C[C@@H]12)c1cccs1 |r| Show InChI InChI=1S/C10H13NS/c1-7-8-5-10(8,6-11-7)9-3-2-4-12-9/h2-4,7-8,11H,5-6H2,1H3/t7-,8+,10+/m1/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at NET in rat brain synaptosome				Bioorg Med Chem Lett 18: 3682-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.077 BindingDB Entry DOI: 10.7270/Q26974G5
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50243992 ((trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3...) Show SMILES C[C@H]1NC[C@]2(C[C@@H]12)c1cccs1 |r| Show InChI InChI=1S/C10H13NS/c1-7-8-5-10(8,6-11-7)9-3-2-4-12-9/h2-4,7-8,11H,5-6H2,1H3/t7-,8+,10+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at cloned DAT in rat brain synaptosome				Bioorg Med Chem Lett 18: 3682-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.077 BindingDB Entry DOI: 10.7270/Q26974G5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50243992 ((trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3...) Show SMILES C[C@H]1NC[C@]2(C[C@@H]12)c1cccs1 |r| Show InChI InChI=1S/C10H13NS/c1-7-8-5-10(8,6-11-7)9-3-2-4-12-9/h2-4,7-8,11H,5-6H2,1H3/t7-,8+,10+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at SERT in rat brain synaptosome				Bioorg Med Chem Lett 18: 3682-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.077 BindingDB Entry DOI: 10.7270/Q26974G5
					More data for this Ligand-Target Pair