BDBM50244225 4-Benzylamino-2-[(4-piperidin-1-ylphenyl)amino]pyrimidine-5-carboxamide::CHEMBL461304

SMILES: NC(=O)c1cnc(Nc2ccc(cc2)N2CCCCC2)nc1NCc1ccccc1

InChI Key: InChIKey=RVPIGKDPXAQVSI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244225 (4-Benzylamino-2-[(4-piperidin-1-ylphenyl)amino]pyr...) Show SMILES NC(=O)c1cnc(Nc2ccc(cc2)N2CCCCC2)nc1NCc1ccccc1 Show InChI InChI=1S/C23H26N6O/c24-21(30)20-16-26-23(28-22(20)25-15-17-7-3-1-4-8-17)27-18-9-11-19(12-10-18)29-13-5-2-6-14-29/h1,3-4,7-12,16H,2,5-6,13-15H2,(H2,24,30)(H2,25,26,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
					More data for this Ligand-Target Pair