BDBM50244292 4-[(3-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide::CHEMBL512874

SMILES: NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1cccc(F)c1

InChI Key: InChIKey=ABZNSYQRQZTTTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244292 (4-[(3-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) Show SMILES NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1cccc(F)c1 Show InChI InChI=1S/C22H23FN6O2/c23-16-3-1-2-15(12-16)13-25-21-19(20(24)30)14-26-22(28-21)27-17-4-6-18(7-5-17)29-8-10-31-11-9-29/h1-7,12,14H,8-11,13H2,(H2,24,30)(H2,25,26,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
					More data for this Ligand-Target Pair