BDBM50244539 1-[5-Nitro-6-(4-sulfamoyl-phenoxy)-pyrimidin-4-yl]-piperidine-4-carboxylic acid ethyl ester::CHEMBL452070

SMILES: CCOC(=O)C1CCN(CC1)c1ncnc(Oc2ccc(cc2)S(N)(=O)=O)c1[N+]([O-])=O

InChI Key: InChIKey=ARZIPPIZQPGTEA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50244539 (1-[5-Nitro-6-(4-sulfamoyl-phenoxy)-pyrimidin-4-yl]...) Show SMILES CCOC(=O)C1CCN(CC1)c1ncnc(Oc2ccc(cc2)S(N)(=O)=O)c1[N+]([O-])=O Show InChI InChI=1S/C18H21N5O7S/c1-2-29-18(24)12-7-9-22(10-8-12)16-15(23(25)26)17(21-11-20-16)30-13-3-5-14(6-4-13)31(19,27)28/h3-6,11-12H,2,7-10H2,1H3,(H2,19,27,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR119 (unknown origin) expressed in HEK293 cells assessed as cAMP level by flash plate assay				J Med Chem 51: 5172-5 (2008) Article DOI: 10.1021/jm8006867 BindingDB Entry DOI: 10.7270/Q2KW5FVB
					More data for this Ligand-Target Pair