BDBM50244682 CHEMBL462197::N-(4-(methylsulfonyl)phenyl)-5-nitro-6-(4-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)pyrimidin-4-amine

SMILES: CS(=O)(=O)c1ccc(Nc2ncnc(N3CCC(CC3)c3nc([n-][o+]3)-c3cccnc3)c2[N+]([O-])=O)cc1

InChI Key: InChIKey=OBUZOPJDMBTCDN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50244682 (CHEMBL462197 | N-(4-(methylsulfonyl)phenyl)-5-nitr...) Show SMILES CS(=O)(=O)c1ccc(Nc2ncnc(N3CCC(CC3)c3nc([n-][o+]3)-c3cccnc3)c2[N+]([O-])=O)cc1 Show InChI InChI=1S/C23H22N8O5S/c1-37(34,35)18-6-4-17(5-7-18)27-21-19(31(32)33)22(26-14-25-21)30-11-8-15(9-12-30)23-28-20(29-36-23)16-3-2-10-24-13-16/h2-7,10,13-15H,8-9,11-12H2,1H3,(H,25,26,27)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	660	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at CPR119 (unknown origin) transfected in Xenopus dermal melanophore assessed as dispersion of melatonin-induced pigmentation				J Med Chem 51: 5172-5 (2008) Article DOI: 10.1021/jm8006867 BindingDB Entry DOI: 10.7270/Q2KW5FVB
					More data for this Ligand-Target Pair