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BDBM50244738 CHEMBL461936::rac-(E/Z)-(4-(3-(trifluoromethyl)benzylidene)-2-(hydroxymethyl)-5-oxo-tetrahydrofuran-2-yl)methyl 2-ethylhexanoate

SMILES: CCCCC(CC)C(=O)OCC1(CO)C\C(=C\c2cccc(c2)C(F)(F)F)C(=O)O1

InChI Key: InChIKey=KOUAZICDPJKIJJ-YVLHZVERSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244738   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase C


(MOUSE)		BDBM50244738
PNG
(CHEMBL461936 | rac-(E/Z)-(4-(3-(trifluoromethyl)be...)
Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C\c2cccc(c2)C(F)(F)F)C(=O)O1
Show InChI InChI=1S/C22H27F3O5/c1-3-5-8-16(4-2)19(27)29-14-21(13-26)12-17(20(28)30-21)10-15-7-6-9-18(11-15)22(23,24)25/h6-7,9-11,16,26H,3-5,8,12-14H2,1-2H3/b17-10-
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Similars
Article
PubMed
 9.40n/an/an/an/an/an/an/an/a



National Cancer Institute at Frederick

Curated by ChEMBL


Assay Description
Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting

J Med Chem 51: 5198-220 (2008)


Article DOI: 10.1021/jm8001907
BindingDB Entry DOI: 10.7270/Q2G44Q4B
More data for this
Ligand-Target Pair