BDBM50244784 2-Methyl-N-(2-methyl-thiazol-5-yl)-5-(3-trifluoromethyl-benzoylamino)-benzamide::CHEMBL461574

SMILES: Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2C)s1

InChI Key: InChIKey=PZWWCIFJQKDZMU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50244784 (2-Methyl-N-(2-methyl-thiazol-5-yl)-5-(3-trifluorom...) Show SMILES Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2C)s1 Show InChI InChI=1S/C20H16F3N3O2S/c1-11-6-7-15(9-16(11)19(28)26-17-10-24-12(2)29-17)25-18(27)13-4-3-5-14(8-13)20(21,22)23/h3-10H,1-2H3,(H,25,27)(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of CSF1R (unknown origin)				Bioorg Med Chem Lett 18: 4794-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.093 BindingDB Entry DOI: 10.7270/Q2028RCC
					More data for this Ligand-Target Pair