BDBM50244842 2-Chloro-N-(2-methyl-thiazol-5-yl)-5-(3-trifluoromethyl-benzoylamino)-benzamide::CHEMBL462132

SMILES: Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2Cl)s1

InChI Key: InChIKey=IKCLEONCNGHCMG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50244842 (2-Chloro-N-(2-methyl-thiazol-5-yl)-5-(3-trifluorom...) Show SMILES Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2Cl)s1 Show InChI InChI=1S/C19H13ClF3N3O2S/c1-10-24-9-16(29-10)26-18(28)14-8-13(5-6-15(14)20)25-17(27)11-3-2-4-12(7-11)19(21,22)23/h2-9H,1H3,(H,25,27)(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of CSF1R (unknown origin)				Bioorg Med Chem Lett 18: 4794-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.093 BindingDB Entry DOI: 10.7270/Q2028RCC
					More data for this Ligand-Target Pair