BDBM50244982 (Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethylene)-tetrahydrofuran-2-yl)methyl 2-propylpentanoate::CHEMBL511847

SMILES: CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2cccnc2)C(=O)O1

InChI Key: InChIKey=AZRVQVNCYCMXGY-YVLHZVERSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAS guanyl releasing protein 3 (Homo sapiens (Human))	BDBM50244982 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2cccnc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-6-16(7-4-2)18(23)25-14-20(13-22)11-17(19(24)26-20)10-15-8-5-9-21-12-15/h5,8-10,12,16,22H,3-4,6-7,11,13-14H2,1-2H3/b17-10-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244982 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2cccnc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-6-16(7-4-2)18(23)25-14-20(13-22)11-17(19(24)26-20)10-15-8-5-9-21-12-15/h5,8-10,12,16,22H,3-4,6-7,11,13-14H2,1-2H3/b17-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair