BDBM50245286 (2R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3-methylbutyl)phenyl)piperazin-1-yl)-2-((tetrahydrofuran-3-yl)methylamino)propan-1-one::CHEMBL462559

SMILES: CC(C)CC(O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NCC1CCOC1

InChI Key: InChIKey=VFZFDRDJVOILGX-LDCMCGJDSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245286 ((2R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3-m...) Show SMILES CC(C)CC(O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NCC1CCOC1 |r| Show InChI InChI=1S/C29H39Cl2N3O3/c1-20(2)15-28(35)24-5-3-4-6-27(24)33-10-12-34(13-11-33)29(36)26(32-18-21-9-14-37-19-21)16-22-7-8-23(30)17-25(22)31/h3-8,17,20-21,26,28,32,35H,9-16,18-19H2,1-2H3/t21?,26-,28?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human MC4 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
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