BDBM50245288 (R)-1-cyclopropyl-3-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxypentan-3-yl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)urea::CHEMBL462009

SMILES: CCC(O)(CC)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)NC1CC1

InChI Key: InChIKey=RHGVJAZZPIBWLX-XMMPIXPASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245288 ((R)-1-cyclopropyl-3-(3-(2,4-dichlorophenyl)-1-(4-(...) Show SMILES CCC(O)(CC)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)NC1CC1 |r| Show InChI InChI=1S/C28H36Cl2N4O3/c1-3-28(37,4-2)22-7-5-6-8-25(22)33-13-15-34(16-14-33)26(35)24(32-27(36)31-21-11-12-21)17-19-9-10-20(29)18-23(19)30/h5-10,18,21,24,37H,3-4,11-17H2,1-2H3,(H2,31,32,36)/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human MC4 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
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