BDBM50245306 CHEMBL4105656

SMILES: CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(c3)S(=O)(=O)NC)ncn2)c1

InChI Key: InChIKey=QWZZLPLERLAQAL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TNNI3K (Homo sapiens (Human))	BDBM50245306 (CHEMBL4105656) Show SMILES CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(c3)S(=O)(=O)NC)ncn2)c1 Show InChI InChI=1S/C18H20N6O4S2/c1-19-29(25,26)15-7-3-5-13(9-15)23-17-11-18(22-12-21-17)24-14-6-4-8-16(10-14)30(27,28)20-2/h3-12,19-20H,1-2H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mammalian ribonucleotide reductase				J Med Chem 61: 3076-3088 (2018) Article DOI: 10.1021/acs.jmedchem.8b00125 BindingDB Entry DOI: 10.7270/Q2Z3221C
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50245306 (CHEMBL4105656) Show SMILES CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(c3)S(=O)(=O)NC)ncn2)c1 Show InChI InChI=1S/C18H20N6O4S2/c1-19-29(25,26)15-7-3-5-13(9-15)23-17-11-18(22-12-21-17)24-14-6-4-8-16(10-14)30(27,28)20-2/h3-12,19-20H,1-2H3,(H2,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin)				J Med Chem 61: 3076-3088 (2018) Article DOI: 10.1021/acs.jmedchem.8b00125 BindingDB Entry DOI: 10.7270/Q2Z3221C
					More data for this Ligand-Target Pair