BDBM50245483 (R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-methylbutanoyl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)-2-methyl-2-(methylamino)propanamide::CHEMBL470301

SMILES: CNC(C)(C)C(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccccc1C(=O)CC(C)C

InChI Key: InChIKey=QKHCLTXQYSRSEK-XMMPIXPASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245483 ((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-methylbut...) Show SMILES CNC(C)(C)C(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccccc1C(=O)CC(C)C |r| Show InChI InChI=1S/C29H38Cl2N4O3/c1-19(2)16-26(36)22-8-6-7-9-25(22)34-12-14-35(15-13-34)27(37)24(33-28(38)29(3,4)32-5)17-20-10-11-21(30)18-23(20)31/h6-11,18-19,24,32H,12-17H2,1-5H3,(H,33,38)/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human MC4 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
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