US11028090, Example 372 {4-[7-(2- methoxy- ethoxy)-1- methyl- [1,2,4]tri- azolo[4,3- a]quinoxaline- 4-ylamino]- butyl}- carbamic acid phenylester

SMILES: COCCOc1ccc2c(c1)nc(NCCCCNC(=O)Oc1ccccc1)c1nnc(C)n21

InChI Key: InChIKey=JNPWZRCPQFSYRK-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 502455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502455 (US11028090, Example 372 | {4-[7-(2- methoxy- ethox...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)Oc1ccccc1)c1nnc(C)n21 Show InChI InChI=1S/C24H28N6O4/c1-17-28-29-23-22(25-12-6-7-13-26-24(31)34-18-8-4-3-5-9-18)27-20-16-19(33-15-14-32-2)10-11-21(20)30(17)23/h3-5,8-11,16H,6-7,12-15H2,1-2H3,(H,25,27)(H,26,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021)
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