BDBM50245836 (rel)-N-((8-(bis(2-chlorophenyl)methyl)-3-(pyridin-2-yl)-8-aza-bicyclo[3.2.1]octan-3-yl)methyl)acetamide::CHEMBL508750

SMILES: CC(=O)NCC1(C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccccn1

InChI Key: InChIKey=GRJYWHVHJJCBMS-SFTDATJTSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50245836 ((rel)-N-((8-(bis(2-chlorophenyl)methyl)-3-(pyridin...) Show SMILES CC(=O)NCC1(C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccccn1 |r,TLB:4:5:12:8.9,28:5:12:8.9| Show InChI InChI=1S/C28H29Cl2N3O/c1-19(34)32-18-28(26-12-6-7-15-31-26)16-20-13-14-21(17-28)33(20)27(22-8-2-4-10-24(22)29)23-9-3-5-11-25(23)30/h2-12,15,20-21,27H,13-14,16-18H2,1H3,(H,32,34)/t20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human cloned nociceptin receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 6340-3 (2008) Article DOI: 10.1016/j.bmcl.2008.10.088 BindingDB Entry DOI: 10.7270/Q2QC0396
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50245836 ((rel)-N-((8-(bis(2-chlorophenyl)methyl)-3-(pyridin...) Show SMILES CC(=O)NCC1(C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccccn1 |r,TLB:4:5:12:8.9,28:5:12:8.9| Show InChI InChI=1S/C28H29Cl2N3O/c1-19(34)32-18-28(26-12-6-7-15-31-26)16-20-13-14-21(17-28)33(20)27(22-8-2-4-10-24(22)29)23-9-3-5-11-25(23)30/h2-12,15,20-21,27H,13-14,16-18H2,1H3,(H,32,34)/t20-,21-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	374	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 6340-3 (2008) Article DOI: 10.1016/j.bmcl.2008.10.088 BindingDB Entry DOI: 10.7270/Q2QC0396
					More data for this Ligand-Target Pair