BDBM50246185 2-(4-(3,4-dichlorophenoxy)-3-((dimethylamino)methyl)phenyl)acetamide::CHEMBL451178

SMILES: CN(C)Cc1cc(CC(N)=O)ccc1Oc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=WNUWIJYSIXZFML-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50246185 (2-(4-(3,4-dichlorophenoxy)-3-((dimethylamino)methy...) Show SMILES CN(C)Cc1cc(CC(N)=O)ccc1Oc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H18Cl2N2O2/c1-21(2)10-12-7-11(8-17(20)22)3-6-16(12)23-13-4-5-14(18)15(19)9-13/h3-7,9H,8,10H2,1-2H3,(H2,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)				Bioorg Med Chem Lett 18: 6088-92 (2008) Article DOI: 10.1016/j.bmcl.2008.10.028 BindingDB Entry DOI: 10.7270/Q2RJ4JBK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50246185 (2-(4-(3,4-dichlorophenoxy)-3-((dimethylamino)methy...) Show SMILES CN(C)Cc1cc(CC(N)=O)ccc1Oc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H18Cl2N2O2/c1-21(2)10-12-7-11(8-17(20)22)3-6-16(12)23-13-4-5-14(18)15(19)9-13/h3-7,9H,8,10H2,1-2H3,(H2,20,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.43	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of serotonin reuptake at SERT (unknown origin)				Bioorg Med Chem Lett 18: 6088-92 (2008) Article DOI: 10.1016/j.bmcl.2008.10.028 BindingDB Entry DOI: 10.7270/Q2RJ4JBK
					More data for this Ligand-Target Pair