BDBM50246208 2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohexanecarboxylic acid::CHEMBL487046::cid_274122
SMILES: OC(=O)C1CCCCC1c1c2ccc(O)c(O)c2oc2c(O)c(=O)ccc12
InChI Key: InChIKey=CAVIJGGXNIURPI-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Heat Shock 70kDa Protein 1 (Homo sapiens (Human)) | BDBM50246208 (2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohex...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2S75DRW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
heat shock 70kDa protein 8 isoform 2 (Homo sapiens (Human)) | BDBM50246208 (2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 4.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q20G3HKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (Homo sapiens) | BDBM50246208 (2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohex...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University Curated by ChEMBL | Assay Description Inhibition of G-protein beta1gamma2 (unknown origin) by flow cytometry | J Med Chem 63: 5013-5030 (2020) Article DOI: 10.1021/acs.jmedchem.9b01452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PH domain leucine-rich repeat-containing protein phosphatase 2 (Homo sapiens (Human)) | BDBM50246208 (2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohex...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California San Diego Curated by ChEMBL | Assay Description Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coli | J Med Chem 53: 6899-911 (2010) Article DOI: 10.1021/jm100331d BindingDB Entry DOI: 10.7270/Q2154H8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Concanavalin-A (Canavalia ensiformis) | BDBM50246208 (2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohex...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Southern University Curated by ChEMBL | Assay Description Inhibition of Canavalia ensiformis concanavalin A binding to yeast mannan by ELLA | Bioorg Med Chem Lett 18: 6573-5 (2008) Article DOI: 10.1016/j.bmcl.2008.09.095 BindingDB Entry DOI: 10.7270/Q2ZW1KRJ | |||||||||||
More data for this Ligand-Target Pair |