BDBM50246254 4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-ylamino)benzamide::CHEMBL488084

SMILES: CC(C)n1c(C)ncc1-c1ccnc(Nc2ccc(cc2)C(N)=O)n1

InChI Key: InChIKey=NQOBQXGFENCWJP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50246254 (4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...) Show SMILES CC(C)n1c(C)ncc1-c1ccnc(Nc2ccc(cc2)C(N)=O)n1 Show InChI InChI=1S/C18H20N6O/c1-11(2)24-12(3)21-10-16(24)15-8-9-20-18(23-15)22-14-6-4-13(5-7-14)17(19)25/h4-11H,1-3H3,(H2,19,25)(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CDK2 (unknown origin)				Bioorg Med Chem Lett 18: 6486-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.075 BindingDB Entry DOI: 10.7270/Q23N2377
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50246254 (4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...) Show SMILES CC(C)n1c(C)ncc1-c1ccnc(Nc2ccc(cc2)C(N)=O)n1 Show InChI InChI=1S/C18H20N6O/c1-11(2)24-12(3)21-10-16(24)15-8-9-20-18(23-15)22-14-6-4-13(5-7-14)17(19)25/h4-11H,1-3H3,(H2,19,25)(H,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 18: 6486-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.075 BindingDB Entry DOI: 10.7270/Q23N2377
					More data for this Ligand-Target Pair