BDBM50246272 (S)-methyl 2-(5,7-dimethyl-3-(2-((R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propanoate::CHEMBL488255

SMILES: COC(=O)[C@H](C)n1c2c(C)cc(C)cc2n(CC(=O)Nc2ccc3C[C@]4(Cc3c2)N(C)C(=O)NC4=O)c1=O

InChI Key: InChIKey=BSJYDQGLLSLMFP-RKOGDMNLSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50246272 ((S)-methyl 2-(5,7-dimethyl-3-(2-((R)-3-methyl-2,5-...) Show SMILES COC(=O)[C@H](C)n1c2c(C)cc(C)cc2n(CC(=O)Nc2ccc3C[C@]4(Cc3c2)N(C)C(=O)NC4=O)c1=O |r| Show InChI InChI=1S/C27H29N5O6/c1-14-8-15(2)22-20(9-14)31(26(37)32(22)16(3)23(34)38-5)13-21(33)28-19-7-6-17-11-27(12-18(17)10-19)24(35)29-25(36)30(27)4/h6-10,16H,11-13H2,1-5H3,(H,28,33)(H,29,35,36)/t16-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK93 cells				Bioorg Med Chem Lett 18: 6122-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.019 BindingDB Entry DOI: 10.7270/Q24Q7TTF
					More data for this Ligand-Target Pair
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50246272 ((S)-methyl 2-(5,7-dimethyl-3-(2-((R)-3-methyl-2,5-...) Show SMILES COC(=O)[C@H](C)n1c2c(C)cc(C)cc2n(CC(=O)Nc2ccc3C[C@]4(Cc3c2)N(C)C(=O)NC4=O)c1=O |r| Show InChI InChI=1S/C27H29N5O6/c1-14-8-15(2)22-20(9-14)31(26(37)32(22)16(3)23(34)38-5)13-21(33)28-19-7-6-17-11-27(12-18(17)10-19)24(35)29-25(36)30(27)4/h6-10,16H,11-13H2,1-5H3,(H,28,33)(H,29,35,36)/t16-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP production				Bioorg Med Chem Lett 18: 6122-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.019 BindingDB Entry DOI: 10.7270/Q24Q7TTF
					More data for this Ligand-Target Pair