BDBM50246315 (R)-2-(3-(2-amino-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide::CHEMBL521076

SMILES: CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4ccccc4n(CC(N)=O)c3=O)cc2C1

InChI Key: InChIKey=LWPGIBBVQYJCSQ-HSZRJFAPSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50246315 ((R)-2-(3-(2-amino-2-oxoethyl)-2-oxo-2,3-dihydro-1H...) Show SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4ccccc4n(CC(N)=O)c3=O)cc2C1 |r| Show InChI InChI=1S/C23H22N6O5/c1-27-21(33)26-20(32)23(27)9-13-6-7-15(8-14(13)10-23)25-19(31)12-29-17-5-3-2-4-16(17)28(22(29)34)11-18(24)30/h2-8H,9-12H2,1H3,(H2,24,30)(H,25,31)(H,26,32,33)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK93 cells				Bioorg Med Chem Lett 18: 6122-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.019 BindingDB Entry DOI: 10.7270/Q24Q7TTF
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50246315 ((R)-2-(3-(2-amino-2-oxoethyl)-2-oxo-2,3-dihydro-1H...) Show SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4ccccc4n(CC(N)=O)c3=O)cc2C1 |r| Show InChI InChI=1S/C23H22N6O5/c1-27-21(33)26-20(32)23(27)9-13-6-7-15(8-14(13)10-23)25-19(31)12-29-17-5-3-2-4-16(17)28(22(29)34)11-18(24)30/h2-8H,9-12H2,1H3,(H2,24,30)(H,25,31)(H,26,32,33)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP production				Bioorg Med Chem Lett 18: 6122-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.019 BindingDB Entry DOI: 10.7270/Q24Q7TTF
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50246315 ((R)-2-(3-(2-amino-2-oxoethyl)-2-oxo-2,3-dihydro-1H...) Show SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4ccccc4n(CC(N)=O)c3=O)cc2C1 |r| Show InChI InChI=1S/C23H22N6O5/c1-27-21(33)26-20(32)23(27)9-13-6-7-15(8-14(13)10-23)25-19(31)12-29-17-5-3-2-4-16(17)28(22(29)34)11-18(24)30/h2-8H,9-12H2,1H3,(H2,24,30)(H,25,31)(H,26,32,33)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP production in presence of...				Bioorg Med Chem Lett 18: 6122-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.019 BindingDB Entry DOI: 10.7270/Q24Q7TTF
					More data for this Ligand-Target Pair