BDBM50246573 4-(4-hydroxyphenyl)-9-methyl-2H-pyrido[3,4-b]indol-1(9H)-one::CHEMBL512392

SMILES: Cn1c2ccccc2c2c(c[nH]c(=O)c12)-c1ccc(O)cc1

InChI Key: InChIKey=TVBLFOLSJWLQNX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50246573 (4-(4-hydroxyphenyl)-9-methyl-2H-pyrido[3,4-b]indol...) Show SMILES Cn1c2ccccc2c2c(c[nH]c(=O)c12)-c1ccc(O)cc1 Show InChI InChI=1S/C18H14N2O2/c1-20-15-5-3-2-4-13(15)16-14(10-19-18(22)17(16)20)11-6-8-12(21)9-7-11/h2-10,21H,1H3,(H,19,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Milano Curated by ChEMBL					Assay Description Inhibition of recombinant RET active protein (unknown origin) by immunoblotting				J Med Chem 51: 7777-87 (2008) Article DOI: 10.1021/jm8007823 BindingDB Entry DOI: 10.7270/Q2DN44X5
					More data for this Ligand-Target Pair