Found 4 hits for monomerid = 50246732 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Insulin receptor
(Homo sapiens (Human)) | BDBM50246732
(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)Show SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:11| Show InChI InChI=1S/C25H23N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,19H,5,11,13-14H2,1H3,(H2,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of General Genetics
Curated by ChEMBL
| Assay Description Inhibition of human INSR |
J Med Chem 51: 7731-6 (2008)
Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50246732
(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)Show SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:11| Show InChI InChI=1S/C25H23N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,19H,5,11,13-14H2,1H3,(H2,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of General Genetics
Curated by ChEMBL
| Assay Description Inhibition of human MET |
J Med Chem 51: 7731-6 (2008)
Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4 |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4
(Homo sapiens (Human)) | BDBM50246732
(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)Show SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:11| Show InChI InChI=1S/C25H23N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,19H,5,11,13-14H2,1H3,(H2,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of General Genetics
Curated by ChEMBL
| Assay Description Inhibition of human CDK4/CycD1 |
J Med Chem 51: 7731-6 (2008)
Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4 |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50246732
(3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...)Show SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:11| Show InChI InChI=1S/C25H23N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,19H,5,11,13-14H2,1H3,(H2,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of General Genetics
Curated by ChEMBL
| Assay Description Inhibition of human CDK2/Cyc2 |
J Med Chem 51: 7731-6 (2008)
Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4 |
More data for this Ligand-Target Pair | |