BDBM50246785 (2E,2'E)-N,N'-(Thiodiethane-2,1-diyl)bis[3-(3,4-dichlorophenyl) acrylamide]::CHEMBL488273

SMILES: Clc1ccc(\C=C\C(=O)NCCSCCNC(=O)\C=C\c2ccc(Cl)c(Cl)c2)cc1Cl

InChI Key: InChIKey=ZTQGUZMRJMYXNB-FCXRPNKRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50246785 ((2E,2'E)-N,N'-(Thiodiethane-2,1-diyl)bis[3-(3,4-di...) Show SMILES Clc1ccc(\C=C\C(=O)NCCSCCNC(=O)\C=C\c2ccc(Cl)c(Cl)c2)cc1Cl Show InChI InChI=1S/C22H20Cl4N2O2S/c23-17-5-1-15(13-19(17)25)3-7-21(29)27-9-11-31-12-10-28-22(30)8-4-16-2-6-18(24)20(26)14-16/h1-8,13-14H,9-12H2,(H,27,29)(H,28,30)/b7-3+,8-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human liver glycogen phosphorylase a in presence of glucose				Bioorg Med Chem 16: 8627-34 (2008) Article DOI: 10.1016/j.bmc.2008.08.010 BindingDB Entry DOI: 10.7270/Q2T72H81
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50246785 ((2E,2'E)-N,N'-(Thiodiethane-2,1-diyl)bis[3-(3,4-di...) Show SMILES Clc1ccc(\C=C\C(=O)NCCSCCNC(=O)\C=C\c2ccc(Cl)c(Cl)c2)cc1Cl Show InChI InChI=1S/C22H20Cl4N2O2S/c23-17-5-1-15(13-19(17)25)3-7-21(29)27-9-11-31-12-10-28-22(30)8-4-16-2-6-18(24)20(26)14-16/h1-8,13-14H,9-12H2,(H,27,29)(H,28,30)/b7-3+,8-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human liver glycogen phosphorylase a in absence of glucose				Bioorg Med Chem 16: 8627-34 (2008) Article DOI: 10.1016/j.bmc.2008.08.010 BindingDB Entry DOI: 10.7270/Q2T72H81
					More data for this Ligand-Target Pair