BDBM50246890 1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine::CHEMBL455718
SMILES: Fc1cccc(F)c1NC(=O)NCc1ccc(cc1)C(=O)N1CCCCc2ccccc12
InChI Key: InChIKey=CHVDHGULKQMPAV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxytocin receptor (Homo sapiens (Human)) | BDBM50246890 (1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]benzoyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vantia Ltd Curated by ChEMBL | Assay Description Binding affinity to oxytocin receptor (unknown origin) | J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50246890 (1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]benzoyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 47 | n/a | n/a | n/a | n/a |
Vantia Ltd Curated by ChEMBL | Assay Description Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report... | J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V | |||||||||||
More data for this Ligand-Target Pair |