BDBM50246924 1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-2-methoxybenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine::CHEMBL455696

SMILES: COc1cc(CNC(=O)Nc2c(F)cccc2F)ccc1C(=O)N1CCCCc2ccccc12

InChI Key: InChIKey=MXJZHZBJXXYPOR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50246924 (1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-2-methox...) Show SMILES COc1cc(CNC(=O)Nc2c(F)cccc2F)ccc1C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C26H25F2N3O3/c1-34-23-15-17(16-29-26(33)30-24-20(27)9-6-10-21(24)28)12-13-19(23)25(32)31-14-5-4-8-18-7-2-3-11-22(18)31/h2-3,6-7,9-13,15H,4-5,8,14,16H2,1H3,(H2,29,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair